Frequency of Mycobacterium tuberculosis Among M. tuberculosis Complex Strains Isolated from Clinical Specimen
Original article Hyunmi Cho1, Jong-Bae Kim2, Young Uh1 1Department of Laboratory Medicine, Wonju Severance Christian Hospital, Yonsei University Wonju College of Medicine, Wonju, 2Department of Biomedical Laboratory Science, College of Health Sciences, Yonsei University, Wonju, Korea Corresponding to Young Uh, E-mail: u931018@yonsei.ac.kr Ann Clin Microbiol 2024;23(1):21-31. https://doi.org/10.5145/ACM.2020.23.1.21Received on 12 June 2019, Revised on 19 August […]
Evaluation of Synergistic Effect of Combined Treatment with Linalool and Colistin on Multidrug-Resistant Acinetobacter baumannii to Expand Candidate for Therapeutic Option
Original article Ung-Jun Kim1, Choon-Mee Kim2, Sook-Jin Jang1, Seul-Bi Lee1, Seong-Sik Cho1, Seok-Hoon Jeong3, Young-Jin Ko1, Seong-Ho Kang1, Geon Park1, Dong-Min Kim4, Na-Ra Yoon4, Young-Joon Ahn5, Dong-hoon Lim6, Joong-Ki Kook7 1Department of Tropical Medicine and Parasitology, Seoul National University College of Medicine, Seoul2Department of Parasitology and Tropical Medicine, Gyeongsang National University College of Medicine, Jinju;3MediCheck […]
Fig. 2. Microbiome of CAPD fluid with 1% cut off of relative abundance.
Ann Clin Microbiol 2020;23:1-10. Application of 16S rRNA Gene-Targeted Next-Generation Sequencing for Bacterial Pathogen Detection in Continuous Ambulatory Peritoneal Dialysis Peritonitis Download image
Fig. 1. Composition of gDNA Mock V34 (1707_C) and MiSeq QC (1903_C) (A), the principal coordinates analysis with CAPD fluid samples with QC controls in each run (B).
Ann Clin Microbiol 2020;23:1-10. Application of 16S rRNA Gene-Targeted Next-Generation Sequencing for Bacterial Pathogen Detection in Continuous Ambulatory Peritoneal Dialysis Peritonitis Download image (A) (B)
Table 1. The comparison of the two methods (culture versus NGS) for the diagnosis of CAPD peritonitis pathogens
Ann Clin Microbiol 2020;23:1-10. Application of 16S rRNA Gene-Targeted Next-Generation Sequencing for Bacterial Pathogen Detection in Continuous Ambulatory Peritoneal Dialysis Peritonitis Download table No Culture NGS (> 10 % relative abundance) Read count Infection Antibiotics* Catheter removal Clear up on day 10 Relapse within 2 months CAPD01 Staphylococcus epidermidis Staphylococcus spp. (20.4 %) 14,841 yes […]
Application of 16S rRNA Gene-Targeted Next-Generation Sequencing for Bacterial Pathogen Detection in Continuous Ambulatory Peritoneal Dialysis Peritonitis

Original article Young Ah Kim1, Ea Wha Kang2, Hye Su Moon4, Daewon Kim3,4, Dongeun Yong3,4 1Department of Laboratory Medicine, 2Department of Internal Medicine, National Health Insurance Service Ilsan Hospital, Goyang, 3Department of Laboratory Medicine, 4Research Institute of Bacterial Resistance, Yonsei University College of Medicine, Seoul, Korea Corresponding to Dongeun Yong, E-mail: deyong@yuhs.ac Ann Clin Microbiol […]
Fig. 2. Morphological analysis of Acanthamoeba spp. using calcofluor-white staining. (A) Acanthamoeba cysts in a group under light microscopy (400×, scale bar = 10 μm). (B) Acanthamoeba trophozoites with a single large nucleus and numerous vacuoles were conspicuous under light microscopy (200×, scale bar = 10 μm). (C) Remarkable Acanthamoeba cysts with double cyst walls under fluorescence microscopy (400×, scale bar = 10 μm). (D) Acanthamoeba trophozoites were relatively unremarkable under fluorescence microscopy (400×, scale bar = 10 μm).
Ann Clin Microbiol 2024;27:149-153. Can Acanthamoeba keratitis be properly diagnosed without culture in the real-world clinical microbiology laboratory?: a case report Download image
Fig. 1. Anterior segment photographs of the patient in this case study. The top two anterior segment images were taken under slit-lamp microscope (A, B) and the bottom two images were under cobalt blue light after fluorescein dye staining (C, D). During the slit-lamp microscopy examination of the patient’s left eye, radial keratoneuritis was observed in the central corneal stroma, while vitreous and retina showed no abnormalities.
Ann Clin Microbiol 2024;27:149-153. Can Acanthamoeba keratitis be properly diagnosed without culture in the real-world clinical microbiology laboratory?: a case report Download image
Fig. 2. The clinical course of dengue shows the three distinct phases (illustration reproduced from Yacoub et al. [23], with permission).
Ann Clin Microbiol 2024;27:131-141. Dengue fever: epidemiology, clinical manifestations, diagnosis, and therapeutic strategies Download image
Fig. 1. Dengue virus transmission cycle (illustration adapted from Gómez et al. [28]).
Ann Clin Microbiol 2024;27:131-141. Dengue fever: epidemiology, clinical manifestations, diagnosis, and therapeutic strategies Download image